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Select Publications

2016. Tan, C.T., Zhou, Q.L., Su, Y.C., Fu, N.Y., Chang, H.C., Tao, R., Sukumaran, S., Baksh, S., Tan, Y., Sabapathy, K., Yu, C.D., and Yu, V. MOAP-1 mediates Fas-induced apoptosis in liver by facilitating tBid recruitment to mitochondria. Cell Reports 16: 174-185.
MOAP-1 mediates Fas-induced apoptosis in liver by facilitating tBid recruitment to mitochondria.
File Size: 3222 kb
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2016. Volodko, N., Salla, M., Zare, A., Abulghasem, E.A., Vincent, K., Benesch, M., McMullen, T., Bathe, O., Postovit, L., and Baksh, S. RASSF1A site-specific methylation hotspots in cancer and correlation with RASSF1C and MOAP-1. Cancers: 8, 55.
RASSF1A site-specific methylation hotspots in cancer and correlation with RASSF1C and MOAP-1
File Size: 8194 kb
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2015. Law, J., Salla, M., Zare, A., Wong, Y., Luong, L., Volodko, N., Svystun, O., Flood, K., Lim, J., Sung, M., Dyck, J., Tan, C.T., Su, Y.C., Yu, V., Mackey, J., and Baksh, S.  Modulator of apoptosis 1 (MOAP-1) is a tumor suppressor protein linked to RASSF1A.  The Journal of Biological Chemistry: 1-35.  
Modulator of Apoptosis 1 (MOAP-1) is a tumor suppressor protein linked to RASSF1A
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2013.  Marilyn Gordon, Mohamed El-Kalla, Yuewen Zhao, Yahya Fiteih, Jennifer Law,Natalia Volodko, Anwar Mohamed, Ayman O. S. El-Kadi, Lei Liu, Jeff Odenbach,  Aducio Thiesen, Christina Onyskiw, Haya Abu Ghazaleh, Jikyoung Park, Sean Bong Lee, Victor C. Yu, Carlos Fernandez-Patron, R. Todd Alexander, Eytan Wine, Shairaz Baksh.  The Tumor Suppressor Gene, RASSF1A, Is Essential forProtection against Inflammation -Induced Injury.  PLoS One: 1-29.  
The Tumor Suppressor Gene, RASSF1A, Is Essential for Protection against Inflammation -Induced Injury.
File Size: 10263 kb
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2014.  Amith, S.R., Wilkinson, J.M., Baksh, S., and Fliegel, L. The Na+/H+ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells. Oncotarget 6: 1262-1275.  
The Na+/H+ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cells.
File Size: 2764 kb
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2014. Aldawsari, F.S., Elshenawy, O.H., El Gendy, M., Aguayo-Ortiz, R., Baksh, S., El-Kadi, A., and Velaquez-Martinez, C.  Design and synthesis of resveratrol-salicylate hybrid derivates as CYP1A1 inhibitors.  Journal of Enzyme Inhibition and Medicinal Chemistry 1-12.
Design and Synthesis of Resveratrol-Salicylate Hybrid Derivatives as CYP1A1 Inhibitors
File Size: 703 kb
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2014. Sandeep S. Dhillon, Ramzi Fattouh, Abdul Elkadri, Wei Xu, Ryan Murchie, Thomas Walters,  Conghui Guo, David Mack, Hien Q. Huynh, Shairaz Baksh, Mark S. Silverberg, Anne M. Griffiths, Scott B. Snapper, John H. Brumell,and Aleixo M. Muise.  Variants in Nicotinamide Adenine Dinucleotide Phosphate Oxidase Complex Components Determine Susceptibility to Very Early Onset Inflammatory Bowel Disease.  Gastroenterology: 680-689. 
Variants in Nicotinamide Adenine Dinucleotide Phosphate Oxidase Complex Components Determine Susceptibility to Very Early Onset Inflammatory Bowel Disease. Gastroenterology 2014.
File Size: 2009 kb
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2014. Baksh, S., and Blandino, G.  Tumor suppression.  FEBS Letter 588: 2557. 
Tumor Suppression
File Size: 198 kb
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2014. Natalia Volodko, Marilyn Gordon, Mohamed Salla, Haya Abu Ghazaleh, Shairaz Baksh.  RASSF tumor suppressor gene family: Biological functions and regulation. FEBS Letter.  2671-2684.
RASSF tumor suppressor gene family: Biological functions and regulation.
File Size: 700 kb
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2014. Dhillon, S., Mastropaolo L., Murchie, R., Griffiths, C., Thoni, C., Elkadri, A., Xu, W., Mack, A., Walters, T., Guo, C., Mack, D., Huynh, H., Baksh. S., Silverberg, M., Brumell, J., Snapper, S., and Muise, A.  Higher activity of the inducible nitric oxide synthase contributes to very early onset of inflammatory bowel disease.  Clinical and Translational Gastroenterology: 2-7.
Higher activity of the inducible nitric oxide synthase contributes to very early onset of inflammatory bowel disease
File Size: 1125 kb
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2012. Clark, G.J., Baksh, S., Latif, F., and Lim, D.S.  RASSF Family Proteins.  Molecular Biology International 2012: 1-2.
RASSF family proteins
File Size: 431 kb
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2012. Jennifer Law, Victor C. Yu, and Shairaz Baksh. Modulators of Apoptosis 1: A Highly Regulated RASSF1A-Interacting BH3-Like Protein.  Molecular Biology International 2012: 1-10.  
Modulators of Apoptosis 1: A Highly Regulated RASSF1A-Interacting BH3-Like Protein
File Size: 1552 kb
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2012. Marilyn Gordon, Mohammed El-Kalla, Shairaz Baksh. RASSF1 Polymorphisms in Cancer.  Molecular Biology International 2012: 1-12.   
RASSF1 Polymorphisms in Cancer
File Size: 892 kb
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2011. Marilyn Gordon, Shairaz Baksh.  RASSF1A: Not a Prototypical Ras Effector.  Small GTPases: 2; 148-157.  
RASSF1A: Not a Prototypical Ras Effector
File Size: 684 kb
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2011.  Shairaz Baksh. Cancer: No Longer a Black Box. In Your Lab: 24-31.
Cancer: No Longer a Black Box
File Size: 669 kb
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2005.  Shairaz Baksh, Stella Tommasi, Sarah Fenton, Victor Yu, Miguel Martins, Gerd Pfeifer, Farida Latif, Julian Downward, Benjamin Neel.  The Tumor Suppressor RASSF1A and MAP-1 Link Death Receptor Signaling To Bax Conformational Change and Cell Death.  Molecular Cell 18: 637-650.  
The Tumor Suppressor RASSF1A and MAP-1 Link Death Receptor Signaling To Bax Conformational Change and Cell Death
File Size: 1561 kb
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2003. Kirsten Lauber, Erwin Bohn, Stefan Martin Krober, Yi-jin Xiao, Sibylle Blumenthal, Ralph Lindemann, Patrizia Marini, Carolin Wiedig, Anke Zobywalski, Shairaz Baksh, Yan Xu, Ingo Autenrieth, Klaus Schulze-Osthoff, Claus Belka, Gernot Stuhler, Sebastian Wesselborg.  Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal.  Cell 113: 717-730.  
Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal
File Size: 691 kb
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2002. Shairaz Baksh, Hans Widlund, Ashley Frazer-Abel, Jinyan Du, Susan Fosmire, David Fisher, James DeCaprio, Jaime Modiano, Steven Burakoff.  NFATc2-Mediated Repression of Cyclin-Dependent Kinase 4 Expression.  Molecular Cell 10: 1071-1081.  
NFATc2-Mediated Repression of Cyclin-Dependent Kinase 4 Expression
File Size: 545 kb
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  • Home
  • About Us
    • Projects
    • Protocols & Reagents
    • Publication
  • Lab Members
  • Prospective Employment
    • Post-Doctoral Fellows
    • Students
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  • Contact
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